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SMAD2 抗体 (AA 97-125)

SMAD2 适用: 人, 小鼠 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032613
发货至: 中国
  • 抗原 See all SMAD2 抗体
    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
    抗原表位
    • 52
    • 42
    • 29
    • 27
    • 23
    • 22
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 97-125
    适用
    • 250
    • 162
    • 130
    • 13
    • 11
    • 10
    • 10
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    人, 小鼠
    宿主
    • 251
    • 11
    克隆类型
    • 225
    • 37
    多克隆
    标记
    • 122
    • 17
    • 12
    • 10
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    This SMAD2 antibody is un-conjugated
    应用范围
    • 205
    • 97
    • 63
    • 54
    • 53
    • 45
    • 43
    • 39
    • 17
    • 15
    • 12
    • 10
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
    交叉反应 (详细)
    Expected species reactivity: Rat, Bovine, Pig, Chicken, Zebrafish, Drosophila
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 97-125 from the human protein was used as the immunogen for this SMAD2 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product SMAD2 Primary Antibody
  • 应用备注
    Titration of the SMAD2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:100,Western blot: 1:1000,Flow Cytometry: 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the SMAD2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
    别名
    SMAD2 (SMAD2 产品)
    背景
    Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. [UniProt]
    UniProt
    Q15796
    途径
    Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
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