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- 抗原 See all SLUG (SNAI2) 抗体
- SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
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抗原表位
- AA 1-30
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLUG antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应 （详细）
- Expected species reactivity: Bovine, Mouse, Rat
- 纯化方法
- Purified
- 免疫原
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this SLUG antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SNAI2 Primary Antibody
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anti-Snail Family Zinc Finger 2 (SNAI2) (AA 97-169) antibody
SNAI2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C12 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 100-200) antibodySNAI2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4B6D5 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 97-169) antibodySNAI2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 98-129) antibodySNAI2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) antibodySNAI2 适用: 人 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 126-268) antibodySNAI2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 89-268) antibodySNAI2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 69-132) antibodySNAI2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (Middle Region) antibodySNAI2 适用: 人, 小鼠, 大鼠, Cow, 绵羊, 兔, 犬, 马, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 12-124) antibodySNAI2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Titration of the SLUG antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the SLUG antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
- 别名
- SLUG (SNAI2) (SNAI2 产品)
- 别名
- Slug antibody, Slugh antibody, Snail2 antibody, snail family transcriptional repressor 2 antibody, snail family zinc finger 2 antibody, Snai2 antibody
- 背景
- SNAI2/SLUG is a transcriptional repressor that modulates both activator-dependent and basal transcription. Involved in the generation and migration of neural crest cells. Plays a role in mediating RAF1-induced transcriptional repression of the TJ protein, occludin (OCLN) and subsequent oncogenic transformation of epithelial cells (By similarity). Represses BRCA2 expression by binding to its E2-box-containing silencer and recruiting CTBP1 and HDAC1 in breast cells. In epidermal keratinocytes, binds to the E-box in ITGA3 promoter and represses its transcription. Involved in the regulation of ITGB1 and ITGB4 expression and cell adhesion and proliferation in epidermal keratinocytes. Binds to E-box2 domain of BSG and activates its expression during TGFB1-induced epithelial-mesenchymal transition (EMT) in hepatocytes. Represses E-Cadherin/CDH1 transcription via E-box elements. Involved in osteoblast maturation. Binds to RUNX2 and SOC9 promoters and may act as a positive and negative transcription regulator, respectively, in osteoblasts. Binds to CXCL12 promoter via E-box regions in mesenchymal stem cells and osteoblasts. Plays an essential role in TWIST1-induced EMT and its ability to promote invasion and metastasis.
- UniProt
- O43623
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