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SKP2 抗体 (AA 156-185)

SKP2 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032602
发货至: 中国
  • 抗原 See all SKP2 抗体
    SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
    抗原表位
    • 16
    • 8
    • 8
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 156-185
    适用
    • 70
    • 36
    • 34
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 63
    • 8
    • 1
    克隆类型
    • 64
    • 7
    多克隆
    标记
    • 41
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SKP2 antibody is un-conjugated
    应用范围
    • 49
    • 20
    • 18
    • 17
    • 13
    • 13
    • 13
    • 12
    • 12
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    纯化方法
    Purified
    免疫原
    A portion of amino acids 156-185 from the human protein was used as the immunogen for this SKP2 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product SKP2 Primary Antibody
  • 应用备注
    Titration of the SKP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the SKP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
    别名
    SKP2 (SKP2 产品)
    别名
    FBXL1 antibody, FBL1 antibody, FLB1 antibody, p45 antibody, RGD1562456 antibody, S-phase kinase-associated protein 2 (p45) antibody, S-phase kinase associated protein 2 antibody, Skp2 antibody, SKP2 antibody
    背景
    SKP2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class, in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas.
    UniProt
    Q13309
    途径
    Mitotic G1-G1/S Phases
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