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REST 抗体 (AA 542-570)
REST
适用: 人
WB, ELISA
宿主: 兔
Polyclonal
unconjugated
REST抗体详情
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抗原
See all REST 抗体
REST
(RE1-Silencing Transcription Factor (REST))
抗原表位
All epitopes for REST 抗体
AA 542-570
适用
All reactivities for REST 抗体
人
宿主
All hosts for REST 抗体
兔
克隆类型
All clonalities for REST 抗体
多克隆
标记
All conjugates for REST 抗体
This REST antibody is un-conjugated
应用范围
All applications for REST 抗体
Western Blotting (WB), ELISA
纯化方法
Antigen affinity purified
免疫原
A portion of amino acids 542-570 from the human protein was used as the immunogen for this REST antibody.
亚型
Ig Fraction
Top Product
Discover our top product REST Primary Antibody
Alternatives
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anti-RE1-Silencing Transcription Factor (REST) (AA 20-69) antibody
REST
适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 猴, Bat, Pig
WB
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
Titration of the REST antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
In 1X PBS, pH 7.4, with 0.09 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the REST antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
REST目标详情
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抗原
REST
(RE1-Silencing Transcription Factor (REST))
别名
REST (REST 产品 )
别名
NRSF antibody, XBR antibody, 2610008J04Rik antibody, AA407358 antibody, xbr antibody, nrsf antibody, rest antibody, resta antibody, REST antibody, RE1 silencing transcription factor antibody, RE1-silencing transcription factor antibody, RE1-silencing transcription factor S homeolog antibody, REST antibody, Rest antibody, rest.S antibody, rest antibody, LOC615792 antibody
背景
Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
UniProt
Q13127
途径
Negative Regulation of Hormone Secretion , Regulation of Hormone Metabolic Process , Regulation of Hormone Biosynthetic Process , Chromatin Binding , Positive Regulation of Endopeptidase Activity
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