Retinoblastoma Protein (Rb) 抗体 (AA 586-615)
-
- 抗原 See all Retinoblastoma Protein (Rb) (Rb Protein) 抗体
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
-
抗原表位
- AA 586-615
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Retinoblastoma Protein (Rb) antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Antigen affinity purified
- 免疫原
- A portion of amino acids 586-615 from the human protein was used as the immunogen for this Rb antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product Rb Protein Primary Antibody
-
-
- 应用备注
- Titration of the Rb antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the Rb antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
- 抗原
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
- 别名
- Rb (Retinoblastoma) (Rb Protein 产品)
- 背景
- The retinoblastoma protein is a tumor suppressor protein that is dysfunctional in many types of cancer. One highly studied function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide. pRb belongs to the pocket protein family, whose members have a pocket for the functional binding of other proteins. Should an oncogenic protein, such as those produced by cells infected by high-risk types of human papillomaviruses, bind and inactivate pRb, this can lead to cancer. Retinoblastoma (Rb) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral.
- UniProt
- P06400
- 途径
- Mitotic G1-G1/S Phases
-