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Retinoblastoma Protein (Rb) 抗体 (AA 586-615)

Rb Protein 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032465
发货至: 中国
  • 抗原 See all Retinoblastoma Protein (Rb) (Rb Protein) 抗体
    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
    抗原表位
    • 16
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    AA 586-615
    适用
    • 179
    • 75
    • 60
    • 8
    • 8
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    • 7
    • 5
    • 3
    • 3
    • 3
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    • 1
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    宿主
    • 155
    • 25
    克隆类型
    • 153
    • 27
    多克隆
    标记
    • 90
    • 17
    • 10
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    • 9
    • 9
    • 6
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    • 6
    This Retinoblastoma Protein (Rb) antibody is un-conjugated
    应用范围
    • 92
    • 92
    • 85
    • 28
    • 26
    • 16
    • 13
    • 9
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 586-615 from the human protein was used as the immunogen for this Rb antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product Rb Protein Primary Antibody
  • 应用备注
    Titration of the Rb antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the Rb antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
    别名
    Rb (Retinoblastoma) (Rb Protein 产品)
    背景
    The retinoblastoma protein is a tumor suppressor protein that is dysfunctional in many types of cancer. One highly studied function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide. pRb belongs to the pocket protein family, whose members have a pocket for the functional binding of other proteins. Should an oncogenic protein, such as those produced by cells infected by high-risk types of human papillomaviruses, bind and inactivate pRb, this can lead to cancer. Retinoblastoma (Rb) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral.
    UniProt
    P06400
    途径
    Mitotic G1-G1/S Phases
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