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PML 抗体 (Sumoylation Site)

PML 适用: 人 WB, IHC, IF, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032330
发货至: 中国
  • 抗原 See all PML 抗体
    PML (Promyelocytic Leukemia (PML))
    抗原表位
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 470-499, Sumoylation Site
    适用
    • 56
    • 10
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 49
    • 10
    克隆类型
    • 49
    • 10
    多克隆
    标记
    • 43
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PML antibody is un-conjugated
    应用范围
    • 50
    • 26
    • 17
    • 16
    • 9
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS)
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 470-499 (sumoylation site) from the human protein was used as the immunogen for this PML antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PML Primary Antibody
  • 应用备注
    Titration of the PML antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the PML antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    PML (Promyelocytic Leukemia (PML))
    别名
    PML (PML 产品)
    别名
    MYL antibody, PP8675 antibody, RNF71 antibody, TRIM19 antibody, 1200009E24Rik antibody, AI661194 antibody, Trim19 antibody, RGD1562602 antibody, PML antibody, promyelocytic leukemia antibody, PML antibody, Pml antibody
    背景
    PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL).
    UniProt
    P29590
    途径
    p53 Pathway, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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