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PKM2 抗体 (AA 476-505)

PKM2 适用: 人, 小鼠, 大鼠, 灵长类 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032237
发货至: 中国
  • 抗原 See all PKM2 抗体
    PKM2 (Pyruvate Kinase M2 (PKM2))
    抗原表位
    • 21
    • 16
    • 16
    • 12
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 476-505
    适用
    • 149
    • 104
    • 92
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 灵长类
    宿主
    • 127
    • 22
    • 5
    克隆类型
    • 133
    • 21
    多克隆
    标记
    • 57
    • 12
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This PKM2 antibody is un-conjugated
    应用范围
    • 85
    • 33
    • 27
    • 27
    • 23
    • 18
    • 15
    • 11
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    纯化方法
    Purified
    免疫原
    A portion of amino acids 476-505 from the human protein was used as the immunogen for this PKM2 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PKM2 Primary Antibody
  • 应用备注
    Titration of the PKM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:200,Western blot: 1:1000,IHC (Paraffin): 1:50-1:1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the PKM2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    PKM2 (Pyruvate Kinase M2 (PKM2))
    别名
    PKM2 (PKM2 产品)
    别名
    CTHBP antibody, OIP3 antibody, PK3 antibody, PKM2 antibody, TCB antibody, THBP1 antibody, AA414905 antibody, AL024370 antibody, AL024424 antibody, Pk-2 antibody, Pk-3 antibody, Pk3 antibody, Pkm2 antibody, PKM12 antibody, PKM antibody, pyruvate kinase M1/2 antibody, pyruvate kinase, muscle antibody, PKM antibody, Pkm antibody
    背景
    PKM2 is a glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. [UniProt]
    UniProt
    P14618
    途径
    Warburg Effect
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