RAPTOR 抗体 (pSer863)
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- 抗原 See all RAPTOR 抗体
- RAPTOR
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抗原表位
- pSer863
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RAPTOR antibody is un-conjugated
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应用范围
- ELISA, Dot Blot (DB)
- 纯化方法
- Antigen affinity purified
- 免疫原
- This phospho-Raptor antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS863 of human Raptor.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product RAPTOR Primary Antibody
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- 应用备注
- Titration of the phospho-Raptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the phospho-Raptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- RAPTOR
- 别名
- Raptor (RAPTOR 产品)
- 背景
- Raptor participates in the FRAP1 pathway and associates in a near stoichiometric ratio with FRAP1 to form a nutrient-sensitive complex (NSC). It plays a pivotal role as a scaffold protein in the FRAP1-signaling pathway and this interaction is essential for the catalyzed phosphorylation of EIF4EBP1. It has a positive role in nutrient-stimulated signaling to the downstream effector RPS6KB1. Under nutrient-deprived conditions, raptor serves as a negative regulator of FRAP1 kinase activity. Regulation of the interaction with FRAP1 is a critical mechanism by which cells coordinate the rate of cell growth and maintenance of cell size with different environmental conditions.
- UniProt
- Q8N122
- 途径
- Warburg Effect
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