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PDX1 抗体 (pThr11)

PDX1 适用: 人 ELISA, DB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032148
发货至: 中国
  • 抗原 See all PDX1 抗体
    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
    抗原表位
    • 20
    • 15
    • 15
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr11
    适用
    • 114
    • 45
    • 34
    • 15
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 127
    • 8
    • 2
    克隆类型
    • 122
    • 15
    多克隆
    标记
    • 61
    • 12
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDX1 antibody is un-conjugated
    应用范围
    • 85
    • 62
    • 32
    • 19
    • 17
    • 14
    • 14
    • 11
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Dot Blot (DB), Immunofluorescence (IF)
    交叉反应 (详细)
    Expected species reactivity: Mouse, Rat
    纯化方法
    Antigen affinity purified
    免疫原
    This phospho-PDX1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT11 of human PDX1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PDX1 Primary Antibody
  • 应用备注
    Titration of the phospho-PDX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:100,Dot blot: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the phospho-PDX1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
    别名
    PDX1 (PDX1 产品)
    别名
    GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody
    背景
    PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this protein are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
    UniProt
    P52945
    途径
    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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