电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

LC3C 抗体 (pSer12)

MAP1LC3C 适用: 人 ELISA, WB, DB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031792
发货至: 中国
  • 抗原 See all LC3C (MAP1LC3C) 抗体
    LC3C (MAP1LC3C) (Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C))
    抗原表位
    • 15
    • 13
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    pSer12
    适用
    • 43
    • 3
    • 2
    宿主
    • 41
    • 1
    • 1
    克隆类型
    • 43
    多克隆
    标记
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LC3C antibody is un-conjugated
    应用范围
    • 32
    • 26
    • 8
    • 7
    • 4
    • 4
    • 1
    • 1
    ELISA, Western Blotting (WB), Dot Blot (DB)
    交叉反应 (详细)
    Expected species reactivity: Bovine, Mouse, Rat
    纯化方法
    Antigen affinity purified
    免疫原
    This phospho-LC3C antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS12 of human LC3C.
    亚型
    Ig Fraction
    Top Product
    Discover our top product MAP1LC3C Primary Antibody
  • 应用备注
    Titration of the phospho-LC3C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Dot blot: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the phospho-LC3C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    LC3C (MAP1LC3C) (Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C))
    别名
    LC3C (MAP1LC3C 产品)
    别名
    MAP1LC3C antibody, MGC154878 antibody, ATG8J antibody, LC3C antibody, microtubule associated protein 1 light chain 3 gamma antibody, microtubule associated protein 1 light chain 3 gamma L homeolog antibody, MAP1LC3C antibody, map1lc3c antibody, map1lc3c.L antibody
    背景
    MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. These proteins are involved in formation of autophagosomal vacuoles (autophagosomes). MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3a is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole).
    UniProt
    Q9H492
    途径
    Autophagy
You are here:
客服