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P-Glycoprotein 抗体 (AA 647-677)

适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032111
发货至: 中国
  • 抗原 See all P-Glycoprotein products
    P-Glycoprotein
    抗原表位
    • 3
    • 2
    • 1
    • 1
    AA 647-677
    适用
    • 20
    • 10
    • 9
    • 2
    宿主
    • 15
    • 6
    克隆类型
    • 14
    • 6
    • 1
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This P-Glycoprotein antibody is un-conjugated
    应用范围
    • 10
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Purified
    免疫原
    A portion of amino acids 647-677 from the human protein was used as the immunogen for this P-Glycoprotein antibody.
    亚型
    Ig Fraction
  • 应用备注
    Titration of the P-Glycoprotein antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the P-Glycoprotein antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    P-Glycoprotein
    Abstract
    P-Glycoprotein 产品
    别名
    ABC20 antibody, CD243 antibody, CLCS antibody, GP170 antibody, MDR1 antibody, P-GP antibody, PGY1 antibody, Abcb1 antibody, Mdr1a antibody, ABCB1 antibody, ABCB4 antibody, CMDR1 antibody, xemdr antibody, ATP binding cassette subfamily B member 1 antibody, ATP binding cassette subfamily B member 1A antibody, ATP binding cassette subfamily B member 1 L homeolog antibody, ABCB1 antibody, Abcb1a antibody, abcb1.L antibody
    背景
    The membrane-associated ABCB1 protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. ABCB1 is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
    UniProt
    P08183
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