NUP50 抗体 (AA 432-461)
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Quick Overview for NUP50 抗体 (AA 432-461) (ABIN3032078)
抗原
See all NUP50 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 432-461
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交叉反应 (详细)
- Expected species reactivity: Rat
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纯化方法
- Purified
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免疫原
- A portion of amino acids 432-461 from the human protein was used as the immunogen for this NUP50 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the NUP50 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the NUP50 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- NUP50 (Nucleoporin 50kDa (NUP50))
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别名
- NUP50
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背景
- The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. NUP50 may serve as a binding site on the nuclear side of the pore complex for export receptor-cargo complexes. It interacts with multiple transport receptor proteins including p27Kip1. This interaction is required for correct intracellular transport and degradation of p27Kip1.
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UniProt
- Q9UKX7
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途径
- Tube Formation
抗原
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