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Nanog 抗体 (AA 15-49)

NANOG 适用: 人 WB, ELISA, IF, IHC, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031942
发货至: 中国
  • 抗原 See all Nanog (NANOG) 抗体
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    抗原表位
    • 16
    • 16
    • 12
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 15-49
    适用
    • 137
    • 58
    • 22
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 126
    • 16
    • 3
    • 1
    克隆类型
    • 121
    • 25
    多克隆
    标记
    • 75
    • 9
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Nanog antibody is un-conjugated
    应用范围
    • 108
    • 60
    • 43
    • 42
    • 26
    • 26
    • 20
    • 18
    • 18
    • 15
    • 8
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    交叉反应 (详细)
    Expected species reactivity: Primate
    纯化方法
    Purified
    免疫原
    A portion of amino acids 15-49 from the human protein was used as the immunogen for this NANOG antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product NANOG Primary Antibody
  • 应用备注
    Titration of the NANOG antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the NANOG antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    别名
    NANOG (NANOG 产品)
    别名
    2410002E02Rik antibody, ENK antibody, ecat4 antibody, NANOG antibody, hacp antibody, wu:fd19e04 antibody, wu:fd20a07 antibody, zgc:193933 antibody, Nanog homeobox antibody, nanog homeobox antibody, Nanog antibody, NANOG antibody, nanog antibody
    背景
    NANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cell proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation. [UniProt]
    UniProt
    Q9H9S0
    途径
    Stem Cell Maintenance
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