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MLH1 抗体 (AA 452-480)

Name: MLH1 抗体 (AA 452-480)
SKU: ABIN3031882
Availability: OutOfStock

MLH1 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

MLH1 antibody western blot analysis in K562 lysate. (MLH1 抗体 (AA 452-480))

MLH1 antibody flow cytometric analysis of K562 cells (green) compared to a negative control (blue). (MLH1 抗体 (AA 452-480))

FACS

3 images

产品编号 ABIN3031882

发货至: 中国

Datasheet as PDF

抗原 See all MLH1 抗体

MLH1 (MutL Homolog 1 (MLH1))
抗原表位
15

9

9

8

7

6

4

4

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 452-480
适用
82

21

21

4

3

2

2

2

2

2

2

2

2

1

1

1
人
宿主
66

16
兔
Compatible Secondaries
克隆类型
61

21
多克隆
标记
47

5

5

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MLH1 antibody is un-conjugated
应用范围
46

34

18

13

13

12

11

8

6

4

3

2

2

2

2

1

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)

纯化方法

Antigen affinity purified

免疫原

A portion of amino acids 452-480 from the human protein was used as the immunogen for this MLH1 antibody.

亚型

Ig Fraction

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MLH1 适用: 人 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-MutL Homolog 1 (MLH1) (Internal Region) antibody
MLH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-MutL Homolog 1 (MLH1) (AA 373-735) antibody
MLH1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Titration of the MLH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

限制

仅限研究用
状态

Liquid

缓冲液

In 1X PBS, pH 7.4, with 0.09 % sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Aliquot the MLH1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原

MLH1 (MutL Homolog 1 (MLH1))

别名

MLH1 (MLH1 产品)

别名

CG11482 antibody, Dmel\\CG11482 antibody, dmlh-1 antibody, dmlh1 antibody, zgc:66301 antibody, MLH1 antibody, LOC100232198 antibody, 1110035C23Rik antibody, AI317206 antibody, AI325952 antibody, AI561766 antibody, COCA2 antibody, FCC2 antibody, HNPCC antibody, HNPCC2 antibody, hMLH1 antibody, mutL homolog 1 antibody, CG11482 gene product from transcript CG11482-RB antibody, mutL homolog 1 S homeolog antibody, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) antibody, DNA mismatch repair protein Mlh1 antibody, MLH1 antibody, Mlh1 antibody, mlh1.S antibody, mlh1 antibody, LOC588545 antibody

背景

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

UniProt

P40692

途径

DNA Damage Repair, Production of Molecular Mediator of Immune Response