MYLK 抗体 (AA 908-938)
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- 抗原 See all MYLK 抗体
- MYLK (Myosin Light Chain Kinase (MYLK))
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抗原表位
- AA 908-938
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MYLK antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应 （详细）
- Expected species reactivity: Rabbit
- 纯化方法
- Purified
- 免疫原
- A portion of amino acids 908-938 from the human protein was used as the immunogen for this MLCK antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product MYLK Primary Antibody
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anti-Myosin Light Chain Kinase (MYLK) (AA 1375-1524) antibody
MYLK 适用: 人, 小鼠 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 7F2B11 unconjugated
anti-Myosin Light Chain Kinase (MYLK) (AA 1684-1884) antibodyMYLK 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Light Chain Kinase (MYLK) (AA 1441-1709) antibodyMYLK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Light Chain Kinase (MYLK) (AA 1765-1914) antibodyMYLK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Light Chain Kinase (MYLK) (AA 923-953), (N-Term) antibodyMYLK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB03067 unconjugated
anti-Myosin Light Chain Kinase (MYLK) (AA 1661-1877) antibodyMYLK 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myosin Light Chain Kinase (MYLK) antibodyMYLK 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Light Chain Kinase (MYLK) (AA 1-992) antibodyMYLK 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Myosin Light Chain Kinase (MYLK) (C-Term) antibodyMYLK 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myosin Light Chain Kinase (MYLK) (AA 290-398) antibodyMYLK 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Titration of the MLCK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the MLCK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- MYLK (Myosin Light Chain Kinase (MYLK))
- 别名
- MLCK (MYLK 产品)
- 别名
- AAT7 antibody, KRP antibody, MLCK antibody, MLCK1 antibody, MLCK108 antibody, MLCK210 antibody, MSTP083 antibody, MYLK1 antibody, smMLCK antibody, 9530072E15Rik antibody, A930019C19Rik antibody, AW489456 antibody, Mlck antibody, SMMLCK antibody, mlck antibody, fj60a06 antibody, mlck1a antibody, mylk antibody, wu:fj60a06 antibody, zmlck1 antibody, myosin light chain kinase antibody, myosin, light polypeptide kinase antibody, myosin, light chain kinase a antibody, MYLK antibody, Mylk antibody, mylka antibody
- 背景
- MLCK, a member of the Ser/Thr protein kinase family, is a calcium/calmodulin-dependent enzyme responsible for smooth muscle contraction via phosphorylation of a specific serine in the N-terminus of myosin light chains (MLC), an event that facilitates myosin interaction with actin filaments. It is a central determinant in the development of vascular permeability and tissue edema formation. In the nervous system it has been shown to control the growth initiation of astrocytic processes in culture and to participate in transmitter release at synapses formed between cultured sympathetic ganglion cells. MLCK acts as a critical participant in signaling sequences that result in fibroblast apoptosis. Smooth muscle and non-muscle isozymes are expressed in a wide variety of adult and fetal tissues and in cultured endothelium with qualitative expression appearing to be neither tissue- nor development-specific. Non-muscle isoform 2 is the dominant splice variant expressed in various tissues. The Telokin isoform, which binds calmodulin, has been found in a wide variety of adult and fetal tissues. MLCK is probably down-regulated by phosphorylation. The protein contains 1 fibronectin type III domain and 9 immunoglobulin-like C2-type domains.
- UniProt
- Q15746
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