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- 抗原 See all MARK1 抗体
- MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))
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抗原表位
- AA 6-40
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MARK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 纯化方法
- Purified
- 免疫原
- A portion of amino acids 6-40 from the human protein was used as the immunogen for this MARK1 antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product MARK1 Primary Antibody
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anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (AA 560-700) antibody
MARK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (N-Term) antibodyMARK1 适用: 人, 猴, 兔, 马 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (N-Term) antibodyMARK1 适用: 人, 猴, 兔, Bat, Cow, 犬 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (Internal Region) antibodyMARK1 适用: 人, 猴, 兔, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (AA 6-40), (N-Term) antibodyMARK1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB8545 unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (Center) antibodyMARK1 适用: 人, 小鼠, 大鼠, 斑马鱼 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) antibodyMARK1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) antibodyMARK1 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (AA 671-700), (C-Term) antibodyMARK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB8547 unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (AA 643-674), (C-Term) antibodyMARK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1272 unconjugated
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- 应用备注
- Titration of the MARK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the MARK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))
- 别名
- MARK1 (MARK1 产品)
- 别名
- MGC80341 antibody, MARK1 antibody, AW491150 antibody, B930025N23Rik antibody, Emk3 antibody, Par-1c antibody, mKIAA1477 antibody, mPar-1c antibody, MARK antibody, Par1c antibody, MAP/microtubule affinity-regulating kinase 1 S homeolog antibody, microtubule affinity regulating kinase 1 antibody, MAP/microtubule affinity-regulating kinase 1 antibody, MAP/microtubule affinity regulating kinase 1 antibody, mark1.S antibody, MARK1 antibody, mark1 antibody, Mark1 antibody
- 背景
- MARK is a family of kinases that is known for its involvement in establishing cell polarity and in phosphorylating tau protein during Alzheimer neurodegeneration. Expression of MARK causes the phosphorylation of MAPs at their KXGS motifs, thereby detaching MAPs from the microtubules and thus facilitating the transport of particles. This occurs without impairing the intrinsic activity of motors because the velocity during active movement remains unchanged. In primary retinal ganglion cells, transfection with tau leads to the inhibition of axonal transport of mitochondria, APP vesicles, and other cell components which leads to starvation of axons and vulnerability against stress. This transport inhibition can be rescued by phosphorylating tau with MARK
- UniProt
- Q9P0L2
- 途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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