LSD1 抗体 (AA 108-142)
-
- 抗原 See all LSD1 (KDM1A) 抗体
- LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
-
抗原表位
- AA 108-142
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This LSD1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Purified
- 免疫原
- A portion of amino acids 108-142 from the human protein was used as the immunogen for this LSD1 antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product KDM1A Primary Antibody
-
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 130-380) antibody
KDM1A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 130-380) antibodyKO Validated KDM1A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 709-876) antibodyKDM1A 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1H2F8 unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 55-263) antibodyKDM1A 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 3F9D2 unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 55-263) antibodyKDM1A 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 3F9A3 unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 753-851) antibodyKDM1A 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E7 unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 819-852) antibodyKDM1A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 819-852), (C-Term) antibodyKDM1A 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7583 unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 100-150) antibodyKDM1A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 1A (KDM1A) antibodyKDM1A 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 1G7 unconjugated Recombinant Antibody
-
- 应用备注
- Titration of the LSD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the LSD1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
- 抗原
- LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
- 别名
- LSD1 (KDM1A 产品)
- 别名
- AOF2 antibody, BHC110 antibody, KDM1 antibody, LSD1 antibody, 1810043O07Rik antibody, AA408884 antibody, Aof2 antibody, D4Ertd478e antibody, Kdm1 antibody, Lsd1 antibody, mKIAA0601 antibody, DKFZp459N2450 antibody, RGD1562975 antibody, aof2 antibody, kdm1 antibody, wu:fb82e06 antibody, wu:fc51a02 antibody, wu:fj36a05 antibody, wu:fj66b06 antibody, KDM1A antibody, lsd1 antibody, xLSD1 antibody, AtLSD1 antibody, F9F13.30 antibody, F9F13_30 antibody, LESION SIMULATING DISEASE antibody, LESION SIMULATING DISEASE 1 antibody, lysine demethylase 1A antibody, lysine (K)-specific demethylase 1A antibody, lysine (K)-specific demethylase 1a antibody, LSD1 zinc finger family protein antibody, KDM1A antibody, Kdm1a antibody, kdm1a antibody, LSD1 antibody
- 背景
- LSD1 is a histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. LSD1 contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. LSD1 demethylates both mono- and tri-methylted 'Lys-4' of histone H3. This protein may play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3 'Lys-4' on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity. It may also demethylate 'Lys-9' of histone H3, a specific tag for epigenetic transcriptional repression, thereby leading to derepression of androgen receptor target genes.
- UniProt
- O60341
- 途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effect
-
