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LRP6 抗体 (AA 1531-1560)

LRP6 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3028807
发货至: 中国
  • 抗原 See all LRP6 抗体
    LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
    抗原表位
    • 22
    • 21
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1531-1560
    适用
    • 64
    • 46
    • 22
    • 1
    宿主
    • 60
    • 3
    • 1
    • 1
    克隆类型
    • 62
    • 3
    多克隆
    标记
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This LRP6 antibody is un-conjugated
    应用范围
    • 48
    • 26
    • 26
    • 17
    • 17
    • 14
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Purified
    免疫原
    A portion of amino acids 1531-1560 from the human protein was used as the immunogen for this LRP6 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product LRP6 Primary Antibody
  • 应用备注
    Titration of the LRP6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the LRP6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
    别名
    LRP6 (LRP6 产品)
    别名
    lrp6-A antibody, Xlrp6 antibody, adcad2 antibody, lrp6 antibody, LRP6 antibody, ADCAD2 antibody, C030016K15Rik antibody, Cd antibody, Gw antibody, LDL receptor related protein 6 antibody, LDL receptor related protein 6 L homeolog antibody, LDL receptor related protein 6 S homeolog antibody, low density lipoprotein receptor-related protein 6 antibody, low-density lipoprotein receptor-related protein 6 antibody, LRP6 antibody, lrp6.L antibody, lrp6.S antibody, lrp6 antibody, Lrp6 antibody, LOC590395 antibody
    背景
    LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis.
    UniProt
    O75581
    途径
    WNT signaling, Tube Formation
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