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LKB1 抗体 (AA 19-48)

STK11 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032541
发货至: 中国
  • 抗原 See all LKB1 (STK11) 抗体
    LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
    抗原表位
    • 27
    • 26
    • 24
    • 19
    • 15
    • 15
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 19-48
    适用
    • 188
    • 126
    • 69
    • 16
    • 15
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 192
    • 10
    克隆类型
    • 195
    • 7
    多克隆
    标记
    • 78
    • 11
    • 9
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    This LKB1 antibody is un-conjugated
    应用范围
    • 139
    • 72
    • 65
    • 65
    • 32
    • 27
    • 19
    • 15
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
    交叉反应 (详细)
    Expected species reactivity: Mouse, Rat, Chicken
    纯化方法
    Purified
    免疫原
    A portion of amino acids 19-48 from the human protein was used as the immunogen for this LKB1 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product STK11 Primary Antibody
  • 应用备注
    Titration of the LKB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the LKB1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
    别名
    LKB1 (STK11 产品)
    别名
    pjs antibody, LKB1 antibody, XEEK1 antibody, Stk11 antibody, PJS antibody, hLKB1 antibody, AA408040 antibody, Lkb1 antibody, Par-4 antibody, R75140 antibody, mLKB1 antibody, wu:fj61a05 antibody, zgc:110180 antibody, xeek1 antibody, serine/threonine kinase 11 antibody, polarization-related protein LKB1 antibody, serine/threonine kinase 11 L homeolog antibody, STK11 antibody, stk11 antibody, LOC662493 antibody, Stk11 antibody, stk11.L antibody
    背景
    LKB1 is a tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal center in response to DNA damage. [UniProt]
    UniProt
    Q15831
    途径
    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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