L1CAM 抗体 (AA 1154-1182)
-
- 抗原 See all L1CAM 抗体
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
-
抗原表位
- AA 1154-1182
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This L1CAM antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 交叉反应 (详细)
- Expected species reactivity: Rat
- 纯化方法
- Antigen affinity purified
- 免疫原
- A portion of amino acids 1154-1182 from the human protein was used as the immunogen for this L1CAM antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product L1CAM Primary Antibody
-
-
- 应用备注
-
Titration of the L1CAM antibody may be required due to differences in protocols and secondary/substrate sensitivity.
1. Cleavage by ADAM10 results in 180 and 40 kDa bands while cleavage by Plasmin results in 140 and 80 kDa bands.\. Western blot: 1:1000 (1)
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the L1CAM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
- 抗原
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
- 别名
- L1CAM (L1CAM 产品)
- 别名
- l1cam-a antibody, CAML1 antibody, CD171 antibody, HSAS antibody, HSAS1 antibody, MASA antibody, MIC5 antibody, N-CAM-L1 antibody, N-CAML1 antibody, NCAM-L1 antibody, S10 antibody, SPG1 antibody, L1 antibody, Hsas antibody, Hyd antibody, NCAML1 antibody, L1 cell adhesion molecule S homeolog antibody, L1 cell adhesion molecule antibody, l1cam.S antibody, L1CAM antibody, L1cam antibody
- 背景
- L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
- UniProt
- P32004
- 途径
- Synaptic Membrane
-