IL-10 抗体 (AA 27-53)
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- 抗原 See all IL-10 (IL10) 抗体
- IL-10 (IL10) (Interleukin 10 (IL10))
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抗原表位
- AA 27-53
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL-10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 交叉反应 (详细)
- Expected species reactivity: Primate
- 纯化方法
- Antigen affinity purified
- 免疫原
- A portion of amino acids 27-53 from the human protein was used as the immunogen for this IL-10 antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product IL10 Primary Antibody
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- 应用备注
- Titration of the IL-10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the IL-10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- IL-10 (IL10) (Interleukin 10 (IL10))
- 别名
- IL-10 (IL10 产品)
- 别名
- CSIF antibody, GVHDS antibody, IL-10 antibody, IL10A antibody, TGIF antibody, Il-10 antibody, IL10X antibody, interleukin 10 antibody, IL10 antibody, Il10 antibody
- 背景
- The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
- UniProt
- P22301
- 途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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