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IGHM 抗体 (AA 103-131)

IGHM 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031293
发货至: 中国
  • 抗原 See all IGHM products
    IGHM (Immunoglobulin Heavy Constant mu (IGHM))
    抗原表位
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 103-131
    适用
    • 25
    • 1
    • 1
    宿主
    • 14
    • 11
    克隆类型
    • 17
    • 8
    多克隆
    标记
    • 21
    • 1
    • 1
    • 1
    • 1
    This IGHM antibody is un-conjugated
    应用范围
    • 12
    • 11
    • 10
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), ELISA
    纯化方法
    Purified
    免疫原
    A portion of amino acids 103-131 from the human protein was used as the immunogen for this IGHM antibody.
    亚型
    Ig Fraction
  • 应用备注
    Titration of the IGHM antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the IGHM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    IGHM (Immunoglobulin Heavy Constant mu (IGHM))
    别名
    IGHM (IGHM 产品)
    别名
    AI326478 antibody, Igh-6 antibody, Igh-M antibody, Igh6 antibody, Igm antibody, muH antibody, ighm1 antibody, wu:fj14a08 antibody, zgc:101769 antibody, AGM1 antibody, MU antibody, VH antibody, immunoglobulin heavy constant mu antibody, Ighm antibody, ighm antibody, IGHM antibody
    背景
    IgM antibodies play an important role in primary defense mechanisms. They have been shown to be involved in early recognition of external invaders like bacteria and viruses, cellular waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions. The membrane-bound form is found in the majority of normal B-cells alongside with IgD. Membrane-bound IgM induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. It may cause death of cells by apoptosis. It is also found in soluble form, which represents about 30 % of the total serum immunoglobulins where it is found almost exclusively as a homopentamer. After the antigen binds to the B-cell receptor, the secreted form is secreted in large amounts. [UniProt]
    UniProt
    P01871
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