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GSK3 beta 抗体 (AA 4-34)

GSK3b 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031095
发货至: 中国
  • 抗原 See all GSK3 beta (GSK3b) 抗体
    GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))
    抗原表位
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 4-34
    适用
    • 6
    • 5
    • 4
    宿主
    • 7
    • 2
    克隆类型
    • 7
    • 2
    多克隆
    标记
    • 9
    This GSK3 beta antibody is un-conjugated
    应用范围
    • 9
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应 (详细)
    Expected species reactivity: Mouse, Rat
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 4-34 from the human protein was used as the immunogen for this GSK3B antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product GSK3b Primary Antibody
  • 应用备注
    Titration of the GSK3B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the GSK3B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))
    别名
    GSK3B (GSK3b 产品)
    别名
    GSK3 antibody, GSK-3 antibody, C86142 antibody, GSK-3beta antibody, 7330414F15Rik antibody, 8430431H08Rik antibody, GSK3beta antibody, fk80d11 antibody, GSK-3[b] antibody, wu:fb68h05 antibody, wu:fk80d11 antibody, gsk-3 antibody, gsk3 antibody, gsk3-beta antibody, gsk3beta antibody, xgsk-3 antibody, glycogen synthase kinase 3 beta antibody, glycogen synthase kinase 3 beta L homeolog antibody, GSK3B antibody, Gsk3b antibody, gsk3b antibody, gsk3b.L antibody
    背景
    GSK3B is a constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. May also mediate the development of insulin resistance by regulating activation of transcription factors. [UniProt]
    UniProt
    P49841
    途径
    WNT signaling, Hedgehog Signaling, Fc-epsilon Receptor Signaling Pathway, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagy, BCR Signaling, Warburg Effect
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