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FBXW7 抗体 (N-Term)

FBXW7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030899
发货至: 中国
  • 抗原 See all FBXW7 抗体
    FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
    抗原表位
    • 15
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 63
    • 35
    • 32
    • 16
    • 15
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 51
    • 13
    克隆类型
    • 54
    • 10
    多克隆
    标记
    • 33
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This FBXW7 antibody is un-conjugated
    应用范围
    • 54
    • 24
    • 14
    • 14
    • 13
    • 11
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antigen affinity purified
    免疫原
    This FBXW7 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 177-208 amino acids from the N-terminal region of human FBXW7.
    亚型
    Ig Fraction
    Top Product
    Discover our top product FBXW7 Primary Antibody
  • 应用备注
    Titration of the FBXW7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the FBXW7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
    别名
    FBXW7 (FBXW7 产品)
    别名
    cdc4 antibody, AGO antibody, CDC4 antibody, FBW6 antibody, FBW7 antibody, FBX30 antibody, FBXO30 antibody, FBXW6 antibody, SEL-10 antibody, SEL10 antibody, hAgo antibody, hCdc4 antibody, 1110001A17Rik antibody, Cdc4 antibody, Fbw7 antibody, Fbwd6 antibody, Fbx30 antibody, Fbxo30 antibody, Fbxw6 antibody, F-box and WD repeat domain containing 7 antibody, F-box and WD-40 domain protein 7 antibody, Fbxw7 antibody, FBXW7 antibody, fbxw7 antibody
    背景
    Substrate recognition component of an SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter bring them to the SCF complex for ubiquitination. Identified substrates include cyclin-E, MYC, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1. [UniProt]
    UniProt
    Q969H0
    途径
    Notch Signaling, EGFR Signaling Pathway
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