-
- 抗原 See all EPR1 抗体
- EPR1 (Early-Phytochrome-Responsive1 (EPR1))
-
抗原表位
- AA 308-337
- 适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This EPR1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Purified
- 免疫原
- A portion of amino acids 308-337 from the human protein was used as the immunogen for this EPR1 antibody.
- 亚型
- Ig Fraction
-
-
- 应用备注
- Titration of the EPR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the EPR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
- 抗原
- EPR1 (Early-Phytochrome-Responsive1 (EPR1))
- 别名
- EPR1 (EPR1 产品)
- 背景
- Cellular receptors for blood proteases regulate chemotaxis, extracellular proteolysis, and growth behavior of normal and malignant cells. Effector cell protease receptor-1 (EPR1) is a receptor for the coagulation protease factor Xa. EPR1 is characterized by a cysteine-rich extracellular module, a single membrane-spanning domain, and a serine-rich cytoplasmic tail featuring at least 15 potential phosphorylation sites. EPR1 also contains 2 N-linked glycosylation sites, 4 O-linked glycosylation sites, and a chondroitin sulfate attachment site, which may provide anchoring for carbohydrate chains, EPR1 transfectants bind to factor Xa in a specific and saturable manner, and in the absence of factor V/Va promote prothrombin activation in a factor Xa concentration-dependent reaction. Activated platelets and megakaryocytes express EPR1. Both EPR1 and membrane-bound factor Va are thought to be required to mediate factor Xa binding to the activated platelet to form a functional prothrombinase complex.
- UniProt
- Q14868
- 途径
- Apoptosis, Cell Division Cycle
-
You are here:
