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EPH Receptor B2 抗体 (AA 1021-1050)

EPHB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030826
发货至: 中国
  • 抗原 See all EPH Receptor B2 (EPHB2) 抗体
    EPH Receptor B2 (EPHB2)
    抗原表位
    • 8
    • 7
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    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    AA 1021-1050
    适用
    • 58
    • 29
    • 13
    • 6
    • 2
    • 1
    • 1
    宿主
    • 46
    • 15
    • 5
    • 2
    克隆类型
    • 48
    • 20
    多克隆
    标记
    • 39
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPH Receptor B2 antibody is un-conjugated
    应用范围
    • 47
    • 45
    • 24
    • 14
    • 10
    • 10
    • 9
    • 2
    • 2
    • 1
    • 1
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Purified
    免疫原
    A portion of amino acids 1021-1050 from the human protein was used as the immunogen for this EphB2 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product EPHB2 Primary Antibody
  • 应用备注
    Titration of the EphB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the EphB2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    EPH Receptor B2 (EPHB2)
    别名
    EphB2 (EPHB2 产品)
    背景
    Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP) through its SH2 domain. It binds RASGAP through the juxtamembrane tyrosines residues, and also interacts with PRKCABP and GRIP1 This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. This protein contains putatively 2 fibronectin type III domains and 1 sterile alpha motif (SAM) domain.
    UniProt
    P29323
    途径
    RTK signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
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