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RCAN1 抗体 (AA 222-252)
RCAN1
适用: 人
WB, ELISA
宿主: 兔
Polyclonal
unconjugated
RCAN1抗体详情
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抗原
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RCAN1
(Regulator of Calcineurin 1 (RCAN1))
抗原表位
All epitopes for RCAN1 抗体
AA 222-252
适用
All reactivities for RCAN1 抗体
人
宿主
All hosts for RCAN1 抗体
兔
克隆类型
All clonalities for RCAN1 抗体
多克隆
标记
All conjugates for RCAN1 抗体
This RCAN1 antibody is un-conjugated
应用范围
All applications for RCAN1 抗体
Western Blotting (WB), ELISA
交叉反应 (详细)
Expected species reactivity: Mouse, Rat, Bovine, Hamster
纯化方法
Purified
免疫原
A portion of amino acids 222-252 from the human protein was used as the immunogen for this DSCR1 antibody.
亚型
Ig Fraction
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使用细节
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应用备注
Titration of the DSCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
In 1X PBS pH 7.4 with 0.09 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the DSCR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
RCAN1目标详情
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抗原
RCAN1
(Regulator of Calcineurin 1 (RCAN1))
别名
DSCR1 (RCAN1 产品 )
别名
ADAPT78 antibody, CSP1 antibody, DSC1 antibody, DSCR1 antibody, MCIP1 antibody, RCN1 antibody, RCAN1 antibody, 2410048A02Rik antibody, AA408855 antibody, AI429645 antibody, AL024459 antibody, AV028423 antibody, Adapt78 antibody, CALP1L antibody, Dscr1 antibody, Mcip1 antibody, dscr1 antibody, rcan1 antibody, wu:fr92c05 antibody, adapt78 antibody, csp1 antibody, dsc1 antibody, mcip1 antibody, MGC53636 antibody, rcn1 antibody, MGC69428 antibody, regulator of calcineurin 1 antibody, regulator of calcineurin 1b antibody, regulator of calcineurin 1 L homeolog antibody, Down syndrome critical region gene 1 antibody, RCAN1 antibody, Rcan1 antibody, rcan1b antibody, rcan1.L antibody, dscr1 antibody, rcan1 antibody
背景
DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. The gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of DSCR1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
UniProt
P53805
途径
Regulation of Muscle Cell Differentiation , Skeletal Muscle Fiber Development
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