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DDR2 抗体

DDR2 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030741
发货至: 中国
  • 抗原 See all DDR2 抗体
    DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
    适用
    • 35
    • 25
    • 2
    • 1
    宿主
    • 41
    • 7
    克隆类型
    • 41
    • 7
    多克隆
    标记
    • 27
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DDR2 antibody is un-conjugated
    应用范围
    • 33
    • 27
    • 20
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    纯化方法
    Purified
    免疫原
    This DDR2 antibody was produced from rabbits immunized with a his tag recombinant protein of human DDR2/TYRO10.
    亚型
    Ig Fraction
    Top Product
    Discover our top product DDR2 Primary Antibody
  • 应用备注
    Titration of the DDR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the DDR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
    别名
    DDR2 (TYRO10) (DDR2 产品)
    别名
    MIG20a antibody, NTRKR3 antibody, TKT antibody, TYRO10 antibody, AW495251 antibody, Ntrkr3 antibody, tyro10 antibody, DDR2 antibody, Tyro10 antibody, ddr2 antibody, si:ch211-193c2.1 antibody, discoidin domain receptor tyrosine kinase 2 antibody, discoidin domain receptor family, member 2 antibody, discoidin domain receptor family, member 2, like antibody, DDR2 antibody, Ddr2 antibody, ddr2l antibody
    背景
    DDR2/TYRO10 is a tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing. [UniProt]
    UniProt
    Q16832
    途径
    RTK signaling
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