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DDR1 抗体 (AA 396-430)

DDR1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030732
发货至: 中国
  • 抗原 See all DDR1 抗体
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    抗原表位
    • 25
    • 15
    • 10
    • 7
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 396-430
    适用
    • 86
    • 41
    • 40
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 94
    • 7
    克隆类型
    • 94
    • 6
    • 1
    多克隆
    标记
    • 42
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DDR1 antibody is un-conjugated
    应用范围
    • 73
    • 36
    • 26
    • 26
    • 22
    • 12
    • 10
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应 (详细)
    Expected species reactivity: Rat
    纯化方法
    Antigen affinity purified
    免疫原
    This DDR1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 396-430 amino acids from the central region of human mouse Ddr1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product DDR1 Primary Antibody
  • 应用备注
    Titration of the DDR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500-1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the DDR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    别名
    DDR1 (DDR1 产品)
    别名
    CG11573 antibody, CG13984 antibody, CG13985 antibody, CG33531 antibody, CG9488 antibody, CG9490 antibody, CT33540 antibody, DDR antibody, Dmel\\CG33531 antibody, Dmel_CG13984 antibody, 6030432F18 antibody, AI323681 antibody, CD167a antibody, Cak antibody, Nep antibody, PTK3A antibody, CAK antibody, CD167 antibody, EDDR1 antibody, HGK2 antibody, MCK10 antibody, NEP antibody, NTRK4 antibody, PTK3 antibody, RTK6 antibody, TRKE antibody, Drd1 antibody, PTK3D antibody, Discoidin domain receptor antibody, discoidin domain receptor family, member 1 antibody, discoidin domain receptor tyrosine kinase 1 antibody, Ddr antibody, Ddr1 antibody, DDR1 antibody
    背景
    Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing, but also tumor cell invasion. Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Phosphorylates PTPN11 (By similarity). Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.
    UniProt
    Q03146
    途径
    RTK signaling, Smooth Muscle Cell Migration
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