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CASP5 抗体 (AA 162-191)

CASP5 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030309
发货至: 中国
  • 抗原 See all CASP5 抗体
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    抗原表位
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 162-191
    适用
    • 43
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 40
    • 3
    克隆类型
    • 33
    • 10
    多克隆
    标记
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This CASP5 antibody is un-conjugated
    应用范围
    • 25
    • 14
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 162-191 from the human protein was used as the immunogen for this Caspase-5 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product CASP5 Primary Antibody
  • 应用备注
    Titration of the Caspase-5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the Caspase-5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    别名
    Caspase-5 (CASP5 产品)
    别名
    ICE(rel)III antibody, ICEREL-III antibody, ICH-3 antibody, CASP5 antibody, caspase 5 antibody, caspase-5 antibody, CASP5 antibody, LOC100437308 antibody
    背景
    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
    UniProt
    P51878
    途径
    Inflammasome
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