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BIM 抗体 (AA 130-165)

BCL2L11 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030147
发货至: 中国
  • 抗原 See all BIM (BCL2L11) 抗体
    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
    抗原表位
    • 15
    • 15
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 130-165
    适用
    • 119
    • 65
    • 56
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 109
    • 8
    • 3
    • 1
    克隆类型
    • 96
    • 25
    多克隆
    标记
    • 65
    • 10
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BIM antibody is un-conjugated
    应用范围
    • 82
    • 46
    • 45
    • 19
    • 19
    • 14
    • 14
    • 13
    • 13
    • 11
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Purified
    免疫原
    A portion of amino acids 130-165 from the human protein was used as the immunogen for this Bim antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product BCL2L11 Primary Antibody
  • 应用备注
    Titration of the Bim antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the Bim antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
    别名
    Bim (BCL2L11 产品)
    背景
    Bim belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bim contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection.
    UniProt
    O43521
    途径
    PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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