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Axin 抗体 (AA 710-738)

AXIN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030087
发货至: 中国
  • 抗原 See all Axin (AXIN1) 抗体
    Axin (AXIN1) (Axin 1 (AXIN1))
    抗原表位
    • 15
    • 15
    • 15
    • 8
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 710-738
    适用
    • 68
    • 59
    • 31
    • 1
    • 1
    宿主
    • 94
    • 6
    • 1
    克隆类型
    • 95
    • 6
    多克隆
    标记
    • 32
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Axin antibody is un-conjugated
    应用范围
    • 71
    • 39
    • 39
    • 36
    • 16
    • 11
    • 9
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 710-738 from the human protein was used as the immunogen for this Axin-1 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product AXIN1 Primary Antibody
  • 应用备注
    Titration of the Axin-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the Axin-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    Axin (AXIN1) (Axin 1 (AXIN1))
    别名
    Axin-1 (AXIN1 产品)
    背景
    Axin-1 is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for the gene.
    UniProt
    O15169
    途径
    WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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