ATG7 抗体 (AA 22-51)
-
- 抗原 See all ATG7 抗体
- ATG7 (ATG7 Autophagy Related 7 (ATG7))
-
抗原表位
- AA 22-51
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ATG7 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 交叉反应 （详细）
- Expected species reactivity: Rat
- 纯化方法
- Antigen affinity purified
- 免疫原
- A portion of amino acids 22-51 from the human protein was used as the immunogen for this ATG7 antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ATG7 Primary Antibody
-
anti-ATG7 Autophagy Related 7 (ATG7) (AA 429-488) antibody
ATG7 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 500-676) antibodyATG7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 477-698) antibodyATG7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 540-569), (C-Term) antibodyATG7 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7474 unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 494-523) antibodyATG7 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (APC)ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal APC
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (Atto 594)ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 594
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (Atto 488)ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 488
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (Atto 390)ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 390
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibodyATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Titration of the ATG7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the ATG7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
- 抗原
- ATG7 (ATG7 Autophagy Related 7 (ATG7))
- 别名
- ATG7 (ATG7 产品)
- 别名
- APG7-LIKE antibody, APG7L antibody, GSA7 antibody, D8 antibody, UBA1B antibody, UBE1L antibody, UBE2 antibody, Ube1l antibody, 1300004C08Rik antibody, AO090001000744 antibody, atg7 antibody, 1810013K23Rik antibody, Agp7 antibody, Apg7l antibody, Atg7l antibody, ATAPG7 antibody, ATATG7 antibody, ATG7 antibody, AUTOPHAGY 7 antibody, AUTOPHAGY-RELATED 7 antibody, K15I22.10 antibody, K15I22_10 antibody, autophagy related 7 antibody, ubiquitin like modifier activating enzyme 7 antibody, ubiquitin-like modifier activating enzyme 7 antibody, autophagy-related protein 7 antibody, Autophagy-related protein 7 antibody, Apg7p antibody, ThiF family protein antibody, ubiquitin-like conjugating enzyme Atg7 antibody, ATG7 antibody, UBA7 antibody, Uba7 antibody, ANI_1_3368024 antibody, AOR_1_1338164 antibody, PTRG_02236 antibody, PAAG_00287 antibody, PITG_12537 antibody, atg7 antibody, Atg7 antibody, APG7 antibody
- 背景
- ATG7 is an E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress. Plays also a key role in the maintenance of axonal homeostasis, the prevention of axonal degeneration, the maintenance of hematopoietic stem cells, the formation of Paneth cell granules, as well as in adipose differentiation. [UniProt]
- UniProt
- O95352
- 途径
- Response to Water Deprivation, Autophagy
-
