ATG12 抗体 (AA 1-50)
-
- 抗原 See all ATG12 抗体
- ATG12 (Autophagy Related 12 (ATG12))
-
抗原表位
- AA 1-50
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ATG12 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 纯化方法
- Antigen affinity purified
- 免疫原
- A portion of amino acids 1-50 from the human protein was used as the immunogen for this ATG12 antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ATG12 Primary Antibody
-
-
- 应用备注
- Titration of the ATG12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:50-1:100
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the ATG12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
- 抗原
- ATG12 (Autophagy Related 12 (ATG12))
- 别名
- ATG12 (ATG12 产品)
- 背景
-
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole).
APG12L/ATG12 is the human homolog of yeast APG12, a ubiquitin-activating enzyme E1-like protein essential for the conjugation system that mediates membrane fusion in autophagy.
- UniProt
- O94817
- 途径
- Autophagy
-