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- 抗原 See all LGR5 抗体
- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
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抗原表位
- AA 605-638
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LGR5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 纯化方法
- Purified
- 免疫原
- A portion of amino acids 605-638 from the human protein was used as the immunogen for this anti-LGR5 antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product LGR5 Primary Antibody
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anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 810-907) antibody
LGR5 适用: 人, 小鼠 WB, FACS, ELISA, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 443-473) antibodyLGR5 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB14555 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 22-178) antibodyLGR5 适用: 人 WB, FACS, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 2B5B9 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 689-719) antibodyLGR5 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal RB14211 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 689-719) antibodyLGR5 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 443-473) antibodyLGR5 适用: 人 WB, FACS, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 250-550) antibodyLGR5 适用: 人, 小鼠 WB, FACS, IHC, IF, IP 宿主: 小鼠 Monoclonal 2A2 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (Cytoplasmic Domain) antibodyLGR5 适用: 人 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 824-907) antibodyLGR5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 241-352) antibodyLGR5 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Titration of the anti-LGR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:10-1:50,Western blot: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the anti-LGR5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
- 别名
- LGR5 (LGR5 产品)
- 别名
- lgr5-a antibody, lgr5a antibody, FEX antibody, Gpr49 antibody, GPR49 antibody, GPR67 antibody, GRP49 antibody, HG38 antibody, leucine-rich repeat containing G protein-coupled receptor 5 L homeolog antibody, leucine rich repeat containing G protein coupled receptor 5 antibody, leucine rich repeat containing G protein-coupled receptor 5 antibody, lgr5.L antibody, Lgr5 antibody, LGR5 antibody
- 背景
- LGR5/GPR49 is a receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development. [UniProt]
- UniProt
- O75473
- 途径
- WNT signaling
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