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APP 抗体 (AA 333-362)

APP 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029927
发货至: 中国
  • 抗原 See all APP 抗体
    APP (Amyloid beta (A4) Precursor Protein (APP))
    抗原表位
    • 30
    • 27
    • 24
    • 20
    • 17
    • 15
    • 11
    • 8
    • 8
    • 7
    • 7
    • 6
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 333-362
    适用
    • 229
    • 110
    • 106
    • 12
    • 10
    • 10
    • 9
    • 9
    • 9
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 194
    • 73
    • 4
    • 4
    • 1
    克隆类型
    • 212
    • 64
    多克隆
    标记
    • 142
    • 24
    • 19
    • 18
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This APP antibody is un-conjugated
    应用范围
    • 177
    • 127
    • 74
    • 52
    • 52
    • 44
    • 38
    • 29
    • 28
    • 15
    • 15
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 333-362 from the human protein was used as the immunogen for this anti-APP antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product APP Primary Antibody
  • 应用备注
    Titration of the anti-APP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the anti-APP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    APP (Amyloid beta (A4) Precursor Protein (APP))
    别名
    APP (APP 产品)
    背景
    The APP gene encodes Amyloid beta, a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
    UniProt
    P05067
    途径
    Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
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