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ACE2 抗体 (AA 59-90)

Name: ACE2 抗体 (AA 59-90)
SKU: ABIN3029962
Availability: OutOfStock

ACE2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

IHC analysis of FFPE human hepatocarcinoma tissue stained with the ACE2 antibody (ACE2 抗体 (AA 59-90))

IHC

Western blot analysis of ACE2 antibody and K562 lysate. (ACE2 抗体 (AA 59-90))

IHC analysis of FFPE human testis tissue stained with ACE2 antibody (ACE2 抗体 (AA 59-90))

IHC

5 images

产品编号 ABIN3029962

发货至: 中国

Datasheet as PDF

抗原 See all ACE2 抗体

ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
抗原表位
16

13

12

8

8

7

6

5

5

4

4

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 59-90
适用
133

52

46

5

4

1

1

1

1

1

1
人
宿主
120

19

6
兔
Compatible Secondaries
克隆类型
110

35
多克隆
标记
73

15

10

8

5

4

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This ACE2 antibody is un-conjugated
应用范围
113

63

47

35

30

19

17

10

10

10

9

6

3

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

纯化方法

Purified

免疫原

A portion of amino acids 59-90 from the human protein was used as the immunogen for this ACE2 antibody.

亚型

Ig Fraction

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ACE2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal AC18F unconjugated

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ACE2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

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ACE2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (N-Term) antibody
Verified ACE2 适用: 人 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 773-805), (C-Term) antibody
ACE2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4819 unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 140-172) antibody
ACE2 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 351-450) antibody
ACE2 适用: 人, 小鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 395-638) antibody
ACE2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Titration of the ACE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

限制

仅限研究用
状态

Liquid

缓冲液

In 1X PBS, pH 7.4, with 0.09 % sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Aliquot the ACE2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原

ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

别名

ACE2 (ACE2 产品)

别名

ACE1 antibody, CD143 antibody, DCP antibody, DCP1 antibody, ICH antibody, MVCD3 antibody, ACEH antibody, 2010305L05Rik antibody, zgc:92514 antibody, angiotensin I converting enzyme antibody, angiotensin I converting enzyme 2 antibody, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 antibody, ACE antibody, ACE2 antibody, Ace2 antibody, ace2 antibody

背景

This gene encodes a deduced 805-amino acid protein containing a potential 17-amino acid N-terminal signal peptide and a putative 22-amino acid C-terminal membrane anchor. It also possesses a zinc metalloprotease consensus sequence and a conserved glutamine residue that may function as a third zinc ligand. ACE2 is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE converts angiotensin I to angiotensin II, ACE2 converts angiotensin I to angiotensin 1-9, which has 9 amino acids. Angiotensin II is a potent blood vessel constrictor, while angiotensin 1-9 does not impact blood vessels but is cleaved by ACE to a shorter peptide, angiotensin 1-7, which is a blood vessel dilator. Spike (S) proteins of coronaviruses, including the SARS coronavirus, bind with cellular receptors to mediate infection of target cells. ACE-2 binds the S1 domain of the SARS coronavirus S protein. SARS coronavirus replicates efficiently on ACE2-transfected but not mock-transfected 293T cells. Anti-ACE-2 but not anti-ACE1 antibody blocks viral replication on Vero E6 cells. It has been proposed that ACE2 is a functional receptor for SARS coronavirus.

UniProt

Q9BYF1

途径

ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour