SIRT1 抗体 (AA 566-601)
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- 抗原 See all SIRT1 抗体
- SIRT1 (Sirtuin 1 (SIRT1))
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抗原表位
- AA 566-601
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIRT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Antigen affinity purified
- 免疫原
- A portion of amino acids 566-601 of the mouse protein was used as the immunogen for the SIRT1 antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SIRT1 Primary Antibody
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anti-Sirtuin 1 (SIRT1) (AA 101-200) antibody
SIRT1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 1 (SIRT1) (AA 456-555) antibodySIRT1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 7B7 unconjugated
anti-Sirtuin 1 (SIRT1) (AA 448-747) antibodySIRT1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 1 (SIRT1) (AA 566-601), (C-Term) antibodySIRT1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB50965 unconjugated
anti-Sirtuin 1 (SIRT1) antibodySIRT1 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-Sirtuin 1 (SIRT1) antibodyKO Validated SIRT1 适用: 人 WB, IHC, IP, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 1 (SIRT1) (N-Term) antibodySIRT1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 斑马鱼, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 1 (SIRT1) (AA 456-555) antibodySIRT1 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 7B7 unconjugated
anti-Sirtuin 1 (SIRT1) (pSer47) antibodySIRT1 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 1 (SIRT1) (AA 244-498) antibodySIRT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- The stated application concentrations are suggested starting points. Titration of the SIRT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:25,Immunofluorescence: 1:25,Western blot: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at 4°C for up to one month. For long term, aliquot the SIRT1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- SIRT1 (Sirtuin 1 (SIRT1))
- 别名
- SIRT1 (SIRT1 产品)
- 别名
- sirtuin 1 antibody, AA673258 antibody, SIR2L1 antibody, Sir2 antibody, Sir2a antibody, Sir2alpha antibody, sir2l1 antibody, sirtuin antibody, SIR2 antibody, sirtuin 1 antibody, sirtuin 1 L homeolog antibody, SIRT1 antibody, SRT1 antibody, Sirt1 antibody, sirt1.L antibody
- 背景
- SIRT1 is a NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression. Deacetylates a broad range of transcription factors and coregulators, thereby regulating target gene expression positively and negatively. [UniProt]
- UniProt
- Q923E4
- 途径
- MAPK Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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