SMAD6 抗体 (AA 358-386)
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- 抗原 See all SMAD6 抗体
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
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抗原表位
- AA 358-386
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMAD6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 交叉反应 （详细）
- Expected species reactivity: Mouse
- 纯化方法
- Antigen affinity purified
- 免疫原
- A portion of amino acids 358-386 from the human protein was used as the immunogen for this SMAD6 antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SMAD6 Primary Antibody
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anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 1-496) antibody
SMAD6 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-384) antibodySMAD6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2A6 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-384) antibodySMAD6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 261-495) antibodySMAD6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 1-496) antibodySMAD6 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 137-182) antibodySMAD6 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-385) antibodySMAD6 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (N-Term) antibodySMAD6 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 357-386), (C-Term) antibodySMAD6 适用: 小鼠 WB 宿主: 兔 Polyclonal RB41931 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) antibodySMAD6 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the SMAD6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at 4°C for up to one month. For long term, aliquot the SMAD6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
- 别名
- SMAD6 (SMAD6 产品)
- 别名
- madh6 antibody, madh7 antibody, Xsmad6 antibody, hst17432 antibody, AOVD2 antibody, HsT17432 antibody, MADH6 antibody, MADH7 antibody, Madh6 antibody, b2b390Clo antibody, Smad6-like antibody, smad6 antibody, wu:fb22g05 antibody, SMAD family member 6 antibody, SMAD family member 6a antibody, smad6 antibody, SMAD6 antibody, Smad6 antibody, smad6a antibody
- 背景
- SMAD6 acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions. [UniProt]
- UniProt
- O43541
- 途径
- Chromatin Binding
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