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TLR7 抗体

TLR7 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4952861
发货至: 中国
  • 抗原 See all TLR7 抗体
    TLR7 (Toll-Like Receptor 7 (TLR7))
    适用
    • 88
    • 41
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 86
    • 16
    克隆类型
    • 78
    • 24
    多克隆
    标记
    • 51
    • 10
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This TLR7 antibody is un-conjugated
    应用范围
    • 57
    • 45
    • 23
    • 14
    • 14
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    纯化方法
    Antigen affinity
    免疫原
    Amino acids QAHPYFWQCLKNALATDNHVAYSQVFKE of human TLR7 were used as the immunogen for the TLR7 antibody.
    亚型
    IgG
    Top Product
    Discover our top product TLR7 Primary Antibody
  • 应用备注
    Optimal dilution of the TLR7 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,Immunocytochemistry: 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the TLR7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    TLR7 (Toll-Like Receptor 7 (TLR7))
    别名
    TLR7 (TLR7 产品)
    别名
    TLR7-like antibody, RGD1563357 antibody, toll like receptor 7 antibody, toll-like receptor 7 antibody, TLR7 antibody, Tlr7 antibody
    背景
    TLR7 (Toll-like receptor 7) is protein that in humans is encoded by the TLR7 gene. Orthologs are found in mammals and birds. TLR7 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on human chromosome X. TLR7 recognises single stranded RNA in endosomes, which is a common feature of viral genomes which are internalised by macrophages.
    UniProt
    Q9NYK1
    途径
    TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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