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ABI1 抗体

This anti-ABI1 antibody is a 兔 多克隆 antibody detecting ABI1 in WB, IHC (p) 和 FACS. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN4952702
发货至: 中国

Quick Overview for ABI1 抗体 (ABIN4952702)

抗原

See all ABI1 抗体
ABI1 (Abl-Interactor 1 (ABI1))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This ABI1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
  • 纯化方法

    Antigen affinity

    免疫原

    Amino acids HGVKWLKAKHGNNQPARTGTLSRTN of human SSH3BP1 were used as the immunogen for the SSH3BP1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the SSH3BP1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the SSH3BP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    ABI1 (Abl-Interactor 1 (ABI1))

    别名

    SSH3BP1

    背景

    SSH3BP1 is also known as ABI1. ABI1 is a human homolog of mouse Abl-interactor-1 (Abi1), mapped on 10p11.2. ABI1 participates in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor (GEF) activities. It dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA, but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins. ABI1 plays a role in the leukemogenesis by translocating to MLL.

    UniProt

    Q8IZP0

    途径

    RTK signaling, Response to Water Deprivation, ER-Nucleus Signaling
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