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ABI1 抗体

ABI1 适用: 人, 大鼠, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4952702
发货至: 中国
  • 抗原 See all ABI1 抗体
    ABI1 (Abl-Interactor 1 (ABI1))
    适用
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    人, 大鼠, 小鼠
    宿主
    • 63
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    克隆类型
    • 63
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    多克隆
    标记
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    This ABI1 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    纯化方法
    Antigen affinity
    免疫原
    Amino acids HGVKWLKAKHGNNQPARTGTLSRTN of human SSH3BP1 were used as the immunogen for the SSH3BP1 antibody.
    亚型
    IgG
    Top Product
    Discover our top product ABI1 Primary Antibody
  • 应用备注
    Optimal dilution of the SSH3BP1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the SSH3BP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    ABI1 (Abl-Interactor 1 (ABI1))
    别名
    SSH3BP1 (ABI1 产品)
    背景
    SSH3BP1 is also known as ABI1. ABI1 is a human homolog of mouse Abl-interactor-1 (Abi1), mapped on 10p11.2. ABI1 participates in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor (GEF) activities. It dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA, but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins. ABI1 plays a role in the leukemogenesis by translocating to MLL.
    UniProt
    Q8IZP0
    途径
    RTK signaling, Response to Water Deprivation, ER-Nucleus Signaling
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