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ATG14 抗体

ATG14 适用: 人, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4950253
发货至: 中国
  • 抗原 See all ATG14 抗体
    ATG14 (ATG14 Autophagy Related 14 (ATG14))
    适用
    • 46
    • 15
    • 7
    • 1
    人, 大鼠
    宿主
    • 38
    • 8
    克隆类型
    • 38
    • 8
    多克隆
    标记
    • 18
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ATG14 antibody is un-conjugated
    应用范围
    • 25
    • 22
    • 15
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    Amino acids RDRERFIDKKERLSRLKSKQEEFQKEVLKAME of human ATG14L were used as the immunogen for the ATG14L antibody.
    亚型
    IgG
    Top Product
    Discover our top product ATG14 Primary Antibody
  • 应用备注
    Optimal dilution of the ATG14L antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the ATG14L antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    ATG14 (ATG14 Autophagy Related 14 (ATG14))
    别名
    ATG14L (ATG14 产品)
    别名
    ATG14L antibody, BARKOR antibody, KIAA0831 antibody, 4832427M01 antibody, Atg14L antibody, D14Ertd114e antibody, D14Ertd436e antibody, RGD1304610 antibody, autophagy related 14 antibody, ATG14 antibody, Atg14 antibody
    背景
    ATG14 (also known as beclin-1-associated autophagy-related key regulator (Barkor) or ATG14L), an essential autophagy-specific regulator of the class III phosphatidylinositol 3-kinase complex, promotes membrane tethering of protein-free liposomes, and enhances hemifusion and full fusion of proteoliposomes reconstituted with the target (t)-SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) syntaxin 17 (STX17) and SNAP29, and the vesicle (v)-SNARE VAMP8 (vesicle-associated membrane protein 8). ATG14 binds to the SNARE core domain of STX17 through its coiled-coil domain, and stabilizes the STX17-SNAP29 binary t-SNARE complex on autophagosomes.
    UniProt
    Q6ZNE5
    途径
    Autophagy
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