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CFTR / Cystic Fibrosis Transmembrane Regulator 抗体

适用: 人 IHC (p), IF, WB 宿主: 小鼠 Monoclonal CFTR-1341 unconjugated
产品编号 ABIN4949562
发货至: 中国
  • 抗原
    CFTR / Cystic Fibrosis Transmembrane Regulator
    适用
    • 9
    • 4
    宿主
    • 5
    • 4
    小鼠
    克隆类型
    • 9
    单克隆
    标记
    • 9
    非结合性
    应用范围
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Western Blotting (WB)
    纯化方法
    Protein G affinity chromatography
    免疫原
    Human recombinant protein was used as the immunogen for this CFTR antibody.
    克隆位点
    CFTR-1341
    亚型
    IgG1
  • 应用备注
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CFTR antibody to be titered up or down for optimal performance.\. Immunofluorescence: 1-2 μg/mL,Western blot: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    1 mg/mL in 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    Store the CFTR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    CFTR / Cystic Fibrosis Transmembrane Regulator
    背景
    Cystic fibrosis transmembrane conductance regulator (CFTR) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (MDR1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
    基因ID
    1080
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