Recombinant CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) 抗体
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- 抗原
- CFTR / Cystic Fibrosis Transmembrane Regulator
- 抗体类型
- Recombinant Antibody
- 抗原表位
- AA 258-385
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- Protein A affinity chromatography
- 免疫原
- A recombinant partial protein corresponding to amino acids 258-385 from the human protein was used as the immunogen for this recombinant CFTR antibody.
- 克隆位点
- CFTR-1775R
- 亚型
- IgG kappa
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anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody
适用: 人 IHC (p), IF, WB 宿主: 小鼠 Monoclonal CFTR-1341 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人, 小鼠 IHC (p) 宿主: 兔 Monoclonal CFTR-2290R unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人, 小鼠 IHC (p) 宿主: 兔 Monoclonal CFTR-2290R unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) antibody适用: 人 IHC (p), IF 宿主: 小鼠 Monoclonal CFTR-1643 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) antibody适用: 人 IHC (p), IF 宿主: 小鼠 Monoclonal CFTR-1643 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人 IHC (p), IF, WB 宿主: 小鼠 Monoclonal CFTR-1341 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人, 小鼠 IHC (p), IF, WB 宿主: 小鼠 Monoclonal SPM176 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator antibody适用: 人, 小鼠 IHC (p), IF, WB 宿主: 小鼠 Monoclonal SPM176 unconjugated
anti-CFTR / Cystic Fibrosis Transmembrane Regulator (AA 258-385) antibody适用: 人 IHC (p), IF 宿主: 兔 Monoclonal CFTR-1775R unconjugated Recombinant Antibody
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- 应用备注
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The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the recombinant CFTR antibody to be titered up or down for optimal performance.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. IF: 1-2 μg/mL,IHC (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1),
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
- 储存液
- Azide free
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store the recombinant CFTR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- 抗原
- CFTR / Cystic Fibrosis Transmembrane Regulator
- 背景
- Recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
- 基因ID
- 1080
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