ORAI3 抗体 (C-Term)
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- 抗原 See all ORAI3 抗体
- ORAI3 (ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3))
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抗原表位
- C-Term
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适用
- 人, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ORAI3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- Recognizes ORAI3. This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI2. Larger molecular weight bands are sometimes seen in SDS-PAGE, these may represent post-translationally modified ORAI3.
- 产品特性
- Synonyms: TMEM142C, ORAI-3, Transmembrane Protein 142C
- 纯化方法
- Immunoaffinity Chromotography.
- 免疫原
- A 19 amino acid peptide from near the carboxy terminus of Human ORAI3
- 克隆位点
- 2H2G9
- 亚型
- IgG
- Top Product
- Discover our top product ORAI3 Primary Antibody
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anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (AA 1-30) antibody
ORAI3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (C-Term) antibodyORAI3 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (N-Term) antibodyORAI3 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (C-Term) antibodyORAI3 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western Blot: ORAI3 antibody can be used for detection of ORAI3 at 2-4 μg/mL. Immunohistochemistry: 2.5 μg/mL. Positive Control: Rat spleen tissue lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- ORAI3 (ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3))
- 别名
- ORAI3 (ORAI3 产品)
- 别名
- ORAI3 antibody, TMEM142C antibody, 9930124N15 antibody, BC061259 antibody, Tmem142c antibody, RGD1306538 antibody, ORAI calcium release-activated calcium modulator 3 antibody, ORAI3 antibody, Orai3 antibody
- 背景
- Antigen stimulation of immune cells triggers Ca++ entry t hrough Ca++ release-activated Ca++ (CRAC) channels. ORAI3 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. However, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, indicating that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2 (5). Na+ currents through ORAI1, 2 and 3 channels were equally inhibited by extracellular Ca++, indicating that each have similar affinities for Ca++ within the selectivity filter.Synonyms: ORAI-3, TMEM142C, Transmembrane Protein 142C
- 基因ID
- 93129
- UniProt
- Q9BRQ5
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