DC-SIGN/CD209 抗体 (Extracellular Domain)
-
- 抗原 See all DC-SIGN/CD209 (CD209) 抗体
- DC-SIGN/CD209 (CD209) (CD209)
-
抗原表位
- Extracellular Domain
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This DC-SIGN/CD209 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- Recognizes CD209 / DC-SIGN.
- 产品特性
- Synonyms: DCSIGN1, DCSIGN, DC-SIGN1, CLEC4L, Dendritic Cell Marker, Dendritic cell-specificICAM-3-grabbing non-integrin 1, C-type lectin domain family 4 member L
- 纯化方法
- Immunoaffinity Chromotography.
- 免疫原
- A recombinant His-tagged protein fragment corresponding to the extracellular region ofHuman DC-SIGN.
- 克隆位点
- 8B6
- 亚型
- IgG
- Top Product
- Discover our top product CD209 Primary Antibody
-
-
- 应用备注
-
ELISA. Western Blot: 1-2 μg/mLImmunohistochemistry: 5-10 μg/mLPositive Controls: Human Uterus Tissue Lysate, Human Lymph Node Tissue Lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
-
Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch. - 有效期
- 12 months
-
- 抗原
- DC-SIGN/CD209 (CD209) (CD209)
- 别名
- CD209 / DC-SIGN (CD209 产品)
- 别名
- CDSIGN antibody, CLEC4L antibody, DC-SIGN antibody, DC-SIGN1 antibody, cd209 antibody, CLEC4M antibody, si:ch211-224h1.3 antibody, CD209 antibody, CIRE antibody, Dcsign antibody, SIGN-R1 antibody, SIGNR5 antibody, Cd209 antibody, CD209 molecule antibody, CD209a antigen antibody, CD209 antigen-like protein D antibody, CD209c molecule antibody, CD209 antigen antibody, CD209 antibody, cd209 antibody, Cd209a antibody, LOC100529184 antibody, Cd209c antibody, LOC100460708 antibody, LOC105484282 antibody
- 背景
- Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes (1), where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN (2). ICAM-3 is the natural ligand for DC-SIGN (3). A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently (4-8). DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR (8). The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1
- 基因ID
- 30835
- UniProt
- Q9NNX6
-