DLG2
适用: 大鼠, 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 350
应用备注
Western blot: 1 μg/mL1 μg/mL was sufficient for detection of Chapsyn-110 in 10 μg of rat brain lysate bycolorimetric immunoblot analysis using Goat anti-mouse IgG: HRP as the secondaryantibody. Immunoprecipitation.1.0-10 μg/mLImmunofluorescence: 1.0-10 μg/mLImmunocytochemistry: 0.1-1.0 μg/mLImmunohistochemistry: 0.1-1.0 μg/mL Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
浓度
1.0 mg/mL
缓冲液
PBS, pH 7.4 containing 50 % Glycerol as stabilizer and 0.09 % Sodium Azide as preservative.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
PPP1R58 antibody, PSD-93 antibody, PSD93 antibody, chapsyn-110 antibody, A330103J02Rik antibody, B230218P12Rik antibody, B330007M19Rik antibody, Dlgh2 antibody, Gm1197 antibody, discs, large homolog 2 (Drosophila) antibody, discs large MAGUK scaffold protein 2 antibody, dlg2 antibody, DLG2 antibody, Dlg2 antibody
背景
Chapsyn-110, is a part of the membrane-associated putative guanylate kinase (MAGUK) family. It binds directly to the NMDA receptor, and Shaker K+ channel subunits, and is 70-80 % identical to PSD-95/SAP90 and SAP97 (1). It associated tightly with the postsynaptic density I brain, and mediates the clustering of both NMDA recpetors and K+ channels in heterologous cells. The encoded protein forms a heterodimer with PSD-95 that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins (1, 2).Synonyms: Channel-associated protein of synapse-110, Chapsyn-110, Disks large homolog 2, PSD-93, Postsynaptic density protein PSD-93