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VRK1 抗体

VRK1 适用: 人 WB 宿主: 小鼠 Monoclonal 5C1 unconjugated
产品编号 ABIN4915154
发货至: 中国
  • 抗原 See all VRK1 抗体
    VRK1 (Vaccinia Related Kinase 1 (VRK1))
    适用
    • 46
    • 10
    • 3
    宿主
    • 40
    • 6
    小鼠
    克隆类型
    • 42
    • 4
    单克隆
    标记
    • 21
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This VRK1 antibody is un-conjugated
    应用范围
    • 38
    • 15
    • 13
    • 13
    • 6
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    纯化方法
    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
    免疫原
    Purified His-tagged VRK1 protein was used to produced this monoclonal antibody.
    克隆位点
    5C1
    亚型
    IgG1
    Top Product
    Discover our top product VRK1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    VRK1 (Vaccinia Related Kinase 1 (VRK1))
    别名
    VRK1 (VRK1 产品)
    别名
    vrk1 antibody, MGC64390 antibody, MGC75762 antibody, VRK1 antibody, PCH1 antibody, PCH1A antibody, 51PK antibody, wu:fe16f06 antibody, zgc:56266 antibody, vaccinia related kinase 1 L homeolog antibody, vaccinia related kinase 1 antibody, Serine/threonine-protein kinase VRK1 antibody, vrk1.L antibody, vrk1 antibody, VRK1 antibody, vrk-1 antibody, Vrk1 antibody
    背景

    Synonyms: PCH1, PCH1A, Serine/threonine-protein kinase VRK1, Vaccinia-related kinase 1, VRK1

    Background: Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity.

    基因ID
    7443
    UniProt
    Q99986
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