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VAMP8 抗体

VAMP8 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 14C3 unconjugated
产品编号 ABIN4915080
发货至: 中国
  • 抗原 See all VAMP8 抗体
    VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))
    适用
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    宿主
    • 40
    • 4
    小鼠
    克隆类型
    • 34
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    单克隆
    标记
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    This VAMP8 antibody is un-conjugated
    应用范围
    • 16
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    纯化方法
    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This VAMP8 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 2~24 amino acids from the N-terminal region of human VAMP8.
    克隆位点
    14C3
    亚型
    IgG1
    Top Product
    Discover our top product VAMP8 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))
    别名
    VAMP8 (VAMP8 产品)
    别名
    vamp8 antibody, EDB antibody, VAMP-8 antibody, AU041171 antibody, Edb antibody, endobrevin antibody, wu:fa18d07 antibody, zgc:56588 antibody, vesicle associated membrane protein 8 antibody, vesicle-associated membrane protein 8 (endobrevin) antibody, vesicle-associated membrane protein 8 antibody, vamp8 antibody, VAMP8 antibody, Vamp8 antibody
    背景

    Synonyms: EDB, VAMP-8, Vesicle-associated membrane protein 8, Endobrevin, VAMP8

    Background: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex (PubMed:23217709, PubMed:25686604). Also required for dense-granule secretion in platelets (PubMed:12130530). Plays also a role in regulated enzyme secretion in pancreatic acinar cells (By similarity). Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells (By similarity). Involved in the homotypic fusion of early and late endosomes (By similarity).

    基因ID
    8673
    UniProt
    Q9BV40
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