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USP5 抗体

USP5 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 13C4 unconjugated
产品编号 ABIN4915071
发货至: 中国
  • 抗原 See all USP5 抗体
    USP5 (Ubiquitin Specific Peptidase 5 (USP5))
    适用
    • 39
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 32
    • 8
    小鼠
    克隆类型
    • 33
    • 7
    单克隆
    标记
    • 25
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This USP5 antibody is un-conjugated
    应用范围
    • 26
    • 17
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This USP5 antibody is generated from a mouse immunized with a recombination protein from the human region of human USP5.
    克隆位点
    13C4
    亚型
    IgG1
    Top Product
    Discover our top product USP5 Primary Antibody
  • 应用备注
    WB 1:300-5000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    USP5 (Ubiquitin Specific Peptidase 5 (USP5))
    别名
    USP5 (USP5 产品)
    别名
    ISOT antibody, AA407472 antibody, ISOT-1 antibody, Ucht antibody, ubiquitin specific peptidase 5 antibody, ubiquitin carboxyl-terminal hydrolase 5 antibody, ubiquitin carboxyl-terminal hydrolase 5, putative antibody, ubiquitin specific protease 5 antibody, ubiquitin specific peptidase 5 (isopeptidase T) antibody, USP5 antibody, CNH02890 antibody, EHI_049940 antibody, CC1G_12961 antibody, MCYG_01862 antibody, CGB_L3600C antibody, PY00546 antibody, Usp5 antibody
    背景

    Synonyms: ISOT, Ubiquitin carboxyl-terminal hydrolase 5, Deubiquitinating enzyme 5, Isopeptidase T, Ubiquitin thioesterase 5, Ubiquitin-specific-processing protease 5, USP5, USP 5, USP-5

    Background: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.

    基因ID
    8078
    UniProt
    P45974
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